2014 - 4 Issue

Case report

Rare Case of Pathological Biomineralization of Eye Tissue

R. A. Moskalenko
A.N. Romanyuk – S.N. Danilchenko – N.I. Kozinets – E.V. Smeyanov – T.G. Kalinichenko – V.N. Kuznetsov

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Published in Czech and Slovak Ophtalmology: 2014 - 4

Published on website: 18.06.2014

Keywords: eye, pathological biomineralization, hydroxyapatite

Summary

The authors have described the case of pathological biomineralization of ocular posterior chamber. Histological examination of affected eye shells revealed inflammation, oedema, dyscirculatory violations, and signs of dystrophic calcification. Structural-phase and chemical analyses of calcification have revealed that the biomineral consists of hydroxyapatite with relatively small crystallite size and defective crystal lattice. In the described case the formation of pathological biomineral in the vision organ was initiated by penetrating wound. Eye injury might have caused a hemophthalmus and chronic inflammatory reaction in the shells, these processes eventually led to the organ subatrophy and to the development of dystrophic and necrobiotic changes in the tissues. Pathological biomineralization in the affected organ developed as a type of dystrophic calcification.

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