Czech and Slovak Ophthalmology 383 10.31348/2025/37 Case report Hyperreflective Outer Nuclear Layer as a Biomarker of Early Stargardt Disease. A Case Report Karti Omer https://orcid.org/0000-0001-5085-0079 Ayhan Ziya https://orcid.org/0000-0002-4385-2196 Saatci Ali Osman https://orcid.org/0000-0001-6848-7239 29 8 2025 5 6

Stargardt disease (STGD1) is among the most prevalent inherited macular dystrophies, characterized by typical flavimaculatus flecks and varying degrees of macular atrophy. This case report highlights the importance of optical coherence tomography (OCT) to detect subtle OCT changes in an 8-year-old girl without any detectable fundus abnormalities.

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