<?xml version="1.0" encoding="UTF-8"?>
<article article-type="research-article" dtd-version="1.3" xml:lang="en">
  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>Czech and Slovak Ophthalmology</journal-title>
      </journal-title-group>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">38</article-id>
      <article-categories>
        <subj-group>
          <subject>Original article</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Pars plicata vitrectomy in premature newborns for retinal detachment as a result of retinopathy of prematurity, our results</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Hejsek</surname>
            <given-names>Libor</given-names>
          </name>
          <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9973-8969</contrib-id>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Kadlecová</surname>
            <given-names>Jana</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Dusová</surname>
            <given-names>Jaroslava</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Macháčková</surname>
            <given-names>Markéta</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Jirásková</surname>
            <given-names>Naďa</given-names>
          </name>
        </contrib>
      </contrib-group>
      <pub-date date-type="pub" publication-format="electronic">
        <day>30</day>
        <month>8</month>
        <year>2017</year>
      </pub-date>
      <issue>4</issue>
      <elocation-id>3</elocation-id>
      <abstract>
        <p>Introduction: The aim of this work is to evaluate our own results of surgical treatment of retinal detachment in immature newborns. Retinopathy of prematurity (ROP) is one of the most complicated ocular disorders, both in terms of diagnosis and therapy. It is a potentially blinding illness that arises from the incomplete development of the bloodstream of the neuroretina of preterm infants. Currently, the most effective therapy is ablation of the avascular retina by laser photocoagulation or cryocoagulation. Despite this treatment, the immature retina may develop it´s detachment. Methodology: We report 2 case-reports, retrospective results of 4-eyes in 2 patients with severe ocular and overall complications of prematurity. The ocular background of preterm babies was investigated in arteficial mydriasis by an indirect ophthalmoscope, and later with the RetCam photographic device. The ROP stages were evaluated according to the ICROP classification. All eyes were treated with cryo-retinopexy at the threshold stage of ROP, followed by intraocular surgery for progression of traction retinal detachment. The surgical technique was a 3-port 25-G PPV (pars-plicata vitrectomy) with insertion of ports 1.5 mm from limbus. The PPV was performed using the Constellation (ALCON) operating unit, controlling the intraocular pressure for 15 torr. The assessment of visual acuity was performed according to the scale: no light perception (no response of the child to light), light sensitivity (positive or negative reaction to illumination), fixation of light. Results: The retina stayed attached in all operated eyes, more in each case-report. Conclusion: Contemporary vitreoretinal surgery allows for the anatomical success of traction retinal detachment surgery during ROP already in neonatal age.</p>
      </abstract>
      <kwd-group>
        <kwd>retinal detachment</kwd>
        <kwd>retinopathy of prematurity</kwd>
        <kwd>PPV</kwd>
        <kwd>surgery</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <back>
    <ref-list>
      <title>References</title>
      <ref id="R8861">
        <mixed-citation>Autrata, R., Holousova, M., Rehurek, J.: Cryotherapy and photocoagulation in the treatment of retinopathy of prematurity. Cesk Slov Oftalmol. 2002 Jan;58(1):30-5.</mixed-citation>
      </ref>
      <ref id="R8862">
        <mixed-citation>Azuma, N., Ishikawa, K., Hama, Y. et al.: Early vitreous surgery for aggressive posterior retinopathy of prematurity. Am J Ophthalmol, 142; 2006: 636–643.</mixed-citation>
      </ref>
      <ref id="R8863">
        <mixed-citation>Capone, A. Jr., Trese, M. T.: Lens-sparing vitreous surgery for tractional stage 4A retinopathy of prematurity retinal detachments. Ophthalmology, 108; 2001: 2068–2070.</mixed-citation>
      </ref>
      <ref id="R8864">
        <mixed-citation>Cryotherapy for Retinopathy of Prematurity Cooperative Group.: Multicenter trial of cryotherapy for retinopathy of prematurity: ophthalmological outcomes at 10 years. Arch Opthalmol., 119; 2001: 1110–1118.</mixed-citation>
      </ref>
      <ref id="R8865">
        <mixed-citation>Early Treatment for Retinopathy of Prematurity Cooperative Group: Revised indication for the treatment of retinopathy of prematurity: results of early treatment for ROP randomized trial. Arch Ophthalmol, 121; 2003: of prematurity. Ophthalmology, 111; 2004: 2271–2273.</mixed-citation>
      </ref>
      <ref id="R8866">
        <mixed-citation>Gilbert, W.S., Quinn, G.E., Dobson, V. et al.: Partial retinal detachment at 3 months after threshold retinopathy of prematurity. Long-term structural and functional outcome. Arch Opthalmol, 114; 1996: 1085–1091.</mixed-citation>
      </ref>
      <ref id="R8867">
        <mixed-citation>Hartnett, M.E.: Features associated with surgical outcome in patients with stages 4 and 5 retinopathy of prematurity. Retina, 23; 2003: 322–329.</mixed-citation>
      </ref>
      <ref id="R8868">
        <mixed-citation>Mintz-Hittner, H.A., O’Malley, R.E., Kretzer, F.L.: Long-term form identification vision after early, closed, lensectomy-vitrectomy for stage 5 retinopathy of prematurity. Ophthalmology, 104; 1997: 454–459.</mixed-citation>
      </ref>
      <ref id="R8869">
        <mixed-citation>Moshfeghi, A.A., Banach, M.J., Salam, G.A. et al.: Lens-sparing vitrectomy for progressive tractional retinal detachments associated with stage 4A retinopathy of prematurity. Arch Ophthalmol, 122; 2004: 1816– 1818.</mixed-citation>
      </ref>
      <ref id="R8870">
        <mixed-citation>Prenner, J.L., Capone, A., Jr., Trese, M.T.: Visual outcomes after lens-sparing vitrectomy for stage 4A retinopathy</mixed-citation>
      </ref>
      <ref id="R8871">
        <mixed-citation>Steinkuller, P.G., Du, L., Gilbert, C. et al.: Childhood blindness. J AAPOS, 3; 1999: 26–32.</mixed-citation>
      </ref>
      <ref id="R8872">
        <mixed-citation>Shulman, J.P., Hobbs, R., Hartnett, M.E.: Retinopathy of Prematurity: Evolving Concepts in Diagnosis and Management. FocalPoints AAO, Vol. XXXIII, N. 7, Jul 2015.</mixed-citation>
      </ref>
      <ref id="R8873">
        <mixed-citation>The Committee for the Classification of Retinopathy of Prematurity. An international classification of retinopathy of prematurity. Arch Ophthalmol., 102; 1984: 1130-4.</mixed-citation>
      </ref>
      <ref id="R8874">
        <mixed-citation>Taylor, D., Hoyt, C.S.: Pediatric ophthalmology and strabismus, 3rd edn. Edinburgh, Scotland: Elsevier Saunders, 2005.</mixed-citation>
      </ref>
      <ref id="R8875">
        <mixed-citation>Yu, X., Qi, Z., Xiaoli, K. et al.: Early vitreoretinal surgery on vascularly active stage 4 retinopathy of prematurity through the preoperative intravitreal bevacizumab injection. Acta Ophthalmol., 91; 2013: 304–310.</mixed-citation>
      </ref>
    </ref-list>
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</article>
